The north-east of the district is part of the Hochschwarzwald, the highest part of the Black Forest. In the west is the Markgräfler Hügelland, in the south the Dinkelberg, both lower hilly areas. The Rhine river, which forms most of the district's southern and western border, is in a narrow valley until it spreads north of Basel in the much wider Oberrheinebene. The district is included in the trinational Basel metropolitan area.
The coat of arms of the Lörrach district can be blazoned as Per fess Argent a Demi Lion facing sinister Gules and in base per pale Or a Bend Gules and Azure a Bend Sinister wavy Argent. The lion in the top part of the coat of arms represents the Lords of Rötteln, who had their primary castle in Loerrach, Wiesental. The bottom-left shows the coat of Baden, as much of the district belonged to the Counts of Baden historically. The wavy line in the bottom-right represents the small river Wiese, which flows through the district.