L-threonine dehydrogenase

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L-Threonine dehydrogenase
Identifiers
EC number1.1.1.103
CAS number9067-99-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
L-Threonine dehydrogenase
Identifiers
SymbolTDH
NCBI gene157739
HGNC15547
RefSeqNM_152566
UniProtQ8IZJ6
Other data
EC number1.1.1.103
LocusChr. 8 p23.1

L-Threonine dehydrogenase is an enzyme that facilitates the catabolism of threonine. It catalyses its conversion to glycine via 2-amino-3-ketobutyrate with concomitant reduction of NAD+.

References[edit]

  • Epperly BR, Dekker EE (April 1991). "L-threonine dehydrogenase from Escherichia coli. Identification of an active site cysteine residue and metal ion studies". The Journal of Biological Chemistry. 266 (10): 6086–92. PMID 2007567.
  • Edgar AJ (October 2002). "The human L-threonine 3-dehydrogenase gene is an expressed pseudogene". BMC Genetics. 3: 18. doi:10.1186/1471-2156-3-18. PMC 131051. PMID 12361482.