LASP1

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LASP1
Protein LASP1 PDB 1zfo.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases LASP1, Lasp-1, MLN50, LIM and SH3 protein 1
External IDs MGI: 109656 HomoloGene: 4480 GeneCards: 3927
RNA expression pattern
PBB GE LASP1 200618 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001271608
NM_006148

NM_010688

RefSeq (protein)

NP_001258537.1
NP_006139.1

NP_034818.1

Location (UCSC) Chr 17: 38.87 – 38.92 Mb Chr 11: 97.8 – 97.84 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

LIM and SH3 domain protein 1 is a protein that in humans is encoded by the LASP1 gene.[3][4]

This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization.[4]

Interactions[edit]

LASP1 has been shown to interact with Zyxin.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Tomasetto C, Regnier C, Moog-Lutz C, Mattei MG, Chenard MP, Lidereau R, Basset P, Rio MC (Jan 1996). "Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17". Genomics. 28 (3): 367–76. doi:10.1006/geno.1995.1163. PMID 7490069. 
  4. ^ a b "Entrez Gene: LASP1 LIM and SH3 protein 1". 
  5. ^ Li, Bo; Zhuang Lei; Trueb Beat (May 2004). "Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1". J. Biol. Chem. United States. 279 (19): 20401–10. doi:10.1074/jbc.M310304200. ISSN 0021-9258. PMID 15004028. 

Further reading[edit]