LBX1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
LBX1
Identifiers
Aliases LBX1, HPX-6, HPX6, LBX1H, homeobox, ladybird homeobox 1
External IDs MGI: 104867 HomoloGene: 4784 GeneCards: LBX1
RNA expression pattern
PBB GE LBX1 208380 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006562

NM_010691

RefSeq (protein)

NP_006553

NP_034821.2
NP_034821

Location (UCSC) Chr 10: 101.23 – 101.23 Mb Chr 19: 45.23 – 45.24 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transcription factor LBX1 is a protein that in humans is encoded by the LBX1 gene.[3][4]

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Jagla K, Dolle P, Mattei MG, Jagla T, Schuhbaur B, Dretzen G, Bellard F, Bellard M (Jul 1996). "Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes". Mech Dev. 53 (3): 345–56. doi:10.1016/0925-4773(95)00450-5. PMID 8645601. 
  4. ^ a b "Entrez Gene: LBX1 ladybird homeobox 1". 

Further reading[edit]