LGR6

From Wikipedia, the free encyclopedia
Jump to: navigation, search
LGR6
Identifiers
Aliases LGR6, GPCR, VTS20631, leucine-rich repeat containing G protein-coupled receptor 6, leucine rich repeat containing G protein-coupled receptor 6
External IDs MGI: 2441805 HomoloGene: 49680 GeneCards: LGR6
RNA expression pattern
PBB GE LGR6 gnf1h10211 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001017403
NM_001017404
NM_021636

NM_001033409

RefSeq (protein)

NP_001017403
NP_001017404
NP_067649

NP_001028581.1
NP_001028581

Location (UCSC) Chr 1: 202.19 – 202.32 Mb Chr 1: 134.98 – 135.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Leucine-rich repeat-containing G-protein coupled receptor 6 is a protein that in humans is encoded by the LGR6 gene.[3][4]

This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Hsu SY, Kudo M, Chen T, Nakabayashi K, Bhalla A, van der Spek PJ, van Duin M, Hsueh AJ (Jan 2001). "The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7". Mol Endocrinol. 14 (8): 1257–71. doi:10.1210/me.14.8.1257. PMID 10935549. 
  4. ^ a b "Entrez Gene: LGR6 leucine-rich repeat-containing G protein-coupled receptor 6". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.