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LIM homeobox 6
Symbols LHX6 ; LHX6.1
External IDs OMIM608215 MGI1306803 HomoloGene7401 GeneCards: LHX6 Gene
RNA expression pattern
PBB GE LHX6 219884 at tn.png
More reference expression data
Species Human Mouse
Entrez 26468 16874
Ensembl ENSG00000106852 ENSMUSG00000026890
UniProt Q9UPM6 Q9R1R0
RefSeq (mRNA) NM_001242333 NM_001083125
RefSeq (protein) NP_001229262 NP_001076594
Location (UCSC) Chr 9:
122.2 – 122.23 Mb
Chr 2:
36.08 – 36.11 Mb
PubMed search [1] [2]

LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.[1][2]

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.[2]


  1. ^ Kimura N, Ueno M, Nakashima K, Taga T (Oct 1999). "A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains". J Biochem 126 (1): 180–7. doi:10.1093/oxfordjournals.jbchem.a022420. PMID 10393337. 
  2. ^ a b "Entrez Gene: LHX6 LIM homeobox 6". 

Further reading[edit]