LHX6

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LHX6
Identifiers
AliasesLHX6, LHX6.1, LIM homeobox 6
External IDsMGI: 1306803 HomoloGene: 7401 GeneCards: LHX6
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for LHX6
Genomic location for LHX6
Band9q33.2Start122,202,577 bp[1]
End122,229,626 bp[1]
RNA expression pattern
PBB GE LHX6 219884 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001083125
NM_001083126
NM_001083127
NM_008500
NM_001355125

RefSeq (protein)

NP_001076594
NP_001076595
NP_001076596
NP_032526
NP_001342054

Location (UCSC)Chr 9: 122.2 – 122.23 MbChr 2: 36.08 – 36.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.[5][6]

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106852 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026890 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Kimura N, Ueno M, Nakashima K, Taga T (Oct 1999). "A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains". J Biochem. 126 (1): 180–7. doi:10.1093/oxfordjournals.jbchem.a022420. PMID 10393337. 
  6. ^ a b "Entrez Gene: LHX6 LIM homeobox 6". 

Further reading[edit]