LHX6

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LHX6
Identifiers
Aliases LHX6, LHX6.1, LIM homeobox 6
External IDs MGI: 1306803 HomoloGene: 7401 GeneCards: 26468
RNA expression pattern
PBB GE LHX6 219884 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001242333
NM_001242334
NM_001242335
NM_014368
NM_199160

NM_001083125
NM_001083126
NM_001083127
NM_008500

RefSeq (protein)

NP_001076595.1
NP_001076596.1
NP_032526.2

Location (UCSC) Chr 9: 122.2 – 122.23 Mb Chr 2: 36.08 – 36.11 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

LIM/homeobox protein Lhx6 is a protein that in humans is encoded by the LHX6 gene.[1][2]

This gene encodes a member of a large protein family that contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and may be involved in the control of differentiation and development of neural and lymphoid cells. Two alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.[2]

References[edit]

  1. ^ Kimura N, Ueno M, Nakashima K, Taga T (Oct 1999). "A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains". J Biochem 126 (1): 180–7. doi:10.1093/oxfordjournals.jbchem.a022420. PMID 10393337. 
  2. ^ a b "Entrez Gene: LHX6 LIM homeobox 6". 

Further reading[edit]