LY-255582

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LY-255582
LY-255,582.svg
Names
IUPAC name
3-{(3R,4R)-1-[(3S)-3-Cyclohexyl-3-hydroxypropyl]-3,4-dimethyl-4-piperidinyl}phenol
Identifiers
ChemSpider 8081850
Jmol-3D images Image
PubChem 9906198
Properties
C22H35NO2
Molar mass 345.53 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]

References[edit]

  1. ^ Dhaher R et al. (Feb 2012). "Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats.". Alcohol. 46 (1): 17–27. doi:10.1016/j.alcohol.2011.08.011. 
  2. ^ Shaw WN et al. (Jun 1991). "The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat.". Int J Obes. 15 (6): 387–95. PMID 1653188.