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Lymphocyte antigen 9
Symbols LY9 ; CD229; SLAMF3; hly9; mLY9
External IDs OMIM600684 MGI96885 HomoloGene1759 GeneCards: LY9 Gene
RNA expression pattern
PBB GE LY9 210370 s at tn.png
PBB GE LY9 215967 s at tn.png
More reference expression data
Species Human Mouse
Entrez 4063 17085
Ensembl ENSG00000122224 ENSMUSG00000004707
UniProt Q9HBG7 Q01965
RefSeq (mRNA) NM_001033667 NM_001277968
RefSeq (protein) NP_001028839 NP_001264897
Location (UCSC) Chr 1:
160.8 – 160.83 Mb
Chr 1:
171.59 – 171.61 Mb
PubMed search [1] [2]

T-lymphocyte surface antigen Ly-9 is a protein that in humans is encoded by the LY9 gene.[1][2][3] LY9 has also recently been designated CD229 (cluster of differentiation 229).


LY9 has been shown to interact with SH2D1A.[4][5]


  1. ^ Sandrin MS, Henning MM, Lo MF, Baker E, Sutherland GR, McKenzie IF (Feb 1996). "Isolation and characterization of cDNA clones for Humly9: the human homologue of mouse Ly9". Immunogenetics 43 (1–2): 13–9. doi:10.1007/bf00186599. PMID 8537117. 
  2. ^ Kingsmore SF, Souryal CA, Watson ML, Patel DD, Seldin MF (Aug 1995). "Physical and genetic linkage of the genes encoding Ly-9 and CD48 on mouse and human chromosomes 1". Immunogenetics 42 (1): 59–62. doi:10.1007/BF00164988. PMID 7797269. 
  3. ^ "Entrez Gene: LY9 lymphocyte antigen 9". 
  4. ^ Sayós J, Martín M, Chen A, Simarro M, Howie D, Morra M et al. (Jun 2001). "Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP". Blood 97 (12): 3867–3874. doi:10.1182/blood.V97.12.3867. PMID 11389028. 
  5. ^ Morra M, Simarro-Grande M, Martin M, Chen AS, Lanyi A, Silander O et al. (Sep 2001). "Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients". J. Biol. Chem. 276 (39): 36809–36816. doi:10.1074/jbc.M101305200. PMID 11477068. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.