Early critical reception to the album has been generally positive and has since gained high acclaim. AllMusic reviewer Gregory Heaney said the band has "found a way to avoid the perils of age and complacency, with the band somehow growing more into its own with each album...the real key to (La Gárgola) lies in open and ambient cuts like album closer "Twinge," where the heaviness is implied with ominous, reverb-drenched guitars and mysterious, almost mantra-like vocal repetition, creating a subtle tension that just can't be accomplished by distorted, in-your-face guitars."Loudwire noted that the experimentation is noticed in the album and comments about the band thinking outside the box. They go on to state "All in all, fans have come to know what to expect from Chevelle and the band definitely deliver on many of the signature sounds they’ve generated over the years."
La Gargola debuted at No. 3 on the Billboard 200 album chart, selling 44,900 copies in the first week and becoming the band's highest charting album. The album has sold 153,000 copies in the United States as of July 2016.