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Lactate aldolase

From Wikipedia, the free encyclopedia
lactate aldolase
Identifiers
EC no.4.1.2.36
CAS no.110777-33-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme lactate aldolase (EC 4.1.2.36) catalyzes the chemical reaction

(S)-lactate formate + acetaldehyde

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-lactate acetaldehyde-lyase (formate-forming). Other names in common use include lactate synthase, and (S)-lactate acetaldehyde-lyase. This enzyme participates in pyruvate metabolism.

References

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  • Gulyi MF, Silonova NV (1987). "[Various metabolic reactions of formate in animal tissues]". Ukr. Biokhim. Zh. 59 (4): 29–35. PMID 3629727.