Lagos bat virus

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Lagos bat virus (LBV)
Virus classification
Group: Group V ((−)ssRNA)
Order: Mononegavirales
Family: Rhabdoviridae
Genus: Lyssavirus
Species: Lagos bat lyssavirus

Lagos bat virus (LBV) is a lyssavirus of southern and central Africa that causes a rabies-like illness in mammals. It was first isolated from a fruit bat (Eidolon helvum) from Lagos Island, Nigeria in 1956.[1] Brain samples from the bat showed poor cross-reactivity to rabies antibodies but the virus was found to be closely related to the rabies virus. This was the first discovery of a rabies-related virus. Until this time, rabies was thought to have a single causal agent.

Lagos bat virus has been isolated from wild and domestic mammals in southern Africa including bats, cats and one dog.[2] One isolate was detected in France in 1999 when a fruit bat (Rousettus egypticus), which had been displaying signs of aggression, died. The bat had been imported from Africa.[3]

No human cases of Lagos bat virus infection have been documented.

References[edit]

  1. ^ Boulger, L. R.; Porterfield, J. S. (September 1958). "Isolation of a Virus from Nigerian Fruit Bats". Transactions of the Royal Society of Tropical Medicine and Hygiene. 52 (5): 421–424. doi:10.1016/0035-9203(58)90127-5. PMID 13592882. 
  2. ^ Markotter, W.; Randles, J.; Rupprecht, C. E.; Sabeta, C. T.; Taylor, P. J.; Wandeler, A. I.; Nel, L. H. (March 2006). "Lagos Bat Virus, South Africa" (pdf). Emerging Infectious Diseases. 12 (3): 504–506. doi:10.3201/eid1205.051306. PMC 3291461Freely accessible. PMID 16704795. 
  3. ^ Picard-Meyer, E.; Barrat, J.; Tissot, E.; Verdot, A.; Patron, C.; Barrat, M. J.; Cliquet, F. (2006). "Bat Rabies Surveillance in France, from 1989 through May 2005". Developments in Biologicals. 125: 283–288. PMID 16878486.