Air is released through 10 distinctive hexagonal holes in the engine cover, while two intakes funnel cool air into the mid-mounted engine compartment. The Sesto Elemento's high power combined with low overall weight translate to a power-to-weight ratio of 0.57 hp/kg (0.26 hp/lb) (with a weight-to-power ratio of 1.75 kg/hp and 3.85 lb/hp). Lamborghini claims a 0–100 km/h (0–62 mph) acceleration time of just 2.5 seconds. Lamborghini sources said that "...they will sell it in very small numbers, in 2013."
The Sesto Elemento's interior is generally minimal with few vehicle comforts such as air-conditioning and car stereo. The seats are built into the chassis of the vechicle, reducing weight and production costs.