Laminin, alpha 1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
LAMA1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases LAMA1, LAMA, S-LAM-alpha, PTBHS, Laminin, alpha 1, laminin subunit alpha 1
External IDs MGI: 99892 HomoloGene: 21146 GeneCards: LAMA1
Genetically Related Diseases
type 2 diabetes mellitus[1]
RNA expression pattern
PBB GE LAMA1 gnf1h07866 at fs.png

PBB GE LAMA1 gnf1h03218 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005559

NM_008480

RefSeq (protein)

NP_005550

NP_032506.2
NP_032506

Location (UCSC) Chr 18: 6.94 – 7.12 Mb Chr 17: 67.7 – 67.82 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Laminin subunit alpha-1 is a protein that in humans is encoded by the LAMA1 gene.[4][5]


Interactions[edit]

Laminin, alpha 1 has been shown to interact with FBLN2.[6][7]

References[edit]

  1. ^ "Diseases that are genetically associated with LAMA1 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Nagayoshi T, Mattei MG, Passage E, Knowlton R, Chu ML, Uitto J (January 1990). "Human laminin A chain (LAMA) gene: chromosomal mapping to locus 18p11.3". Genomics. 5 (4): 932–5. doi:10.1016/0888-7543(89)90136-5. PMID 2591971. 
  5. ^ "Entrez Gene: LAMA1 laminin, alpha 1". 
  6. ^ Utani, A; Nomizu M; Yamada Y (January 1997). "Fibulin-2 binds to the short arms of laminin-5 and laminin-1 via conserved amino acid sequences". J. Biol. Chem. UNITED STATES. 272 (5): 2814–20. doi:10.1074/jbc.272.5.2814. ISSN 0021-9258. PMID 9006922. 
  7. ^ Talts, J F; Sasaki T; Miosge N; Göhring W; Mann K; Mayne R; Timpl R (November 2000). "Structural and functional analysis of the recombinant G domain of the laminin alpha4 chain and its proteolytic processing in tissues". J. Biol. Chem. UNITED STATES. 275 (45): 35192–9. doi:10.1074/jbc.M003261200. ISSN 0021-9258. PMID 10934193. 

Further reading[edit]