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Systematic (IUPAC) name
Clinical data
Routes of
Legal status
Legal status
  • Non-regulated
CAS Number 142139-60-4 YesY
ATC code None
PubChem CID 9847295
ChemSpider 8023009 YesY
UNII T50SJ23G82 YesY
Chemical data
Formula C29H40N2O3
Molar mass 464.6395 g/mol

Lapisteride (INN; CS-891) is a dual inhibitor of both isoforms of the enzyme 5α-reductase.[2] It was under investigation for the treatment of benign prostatic hyperplasia (BPH) and androgenic alopecia,[2][3] but was never marketed.

See also[edit]


  1. ^ Yada S, Ohya M, Ohuchi Y, et al. (April 2003). "Solid phase transition of CS-891 enantiotropes during grinding". International Journal of Pharmaceutics. 255 (1-2): 69–79. doi:10.1016/S0378-5173(03)00084-X. PMID 12672603. 
  2. ^ a b Niiyama S, Kojima K, Hamada T, Happle R, Hoffmann R (December 2000). "The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles". European Journal of Dermatology. 10 (8): 593–5. PMID 11125319. 
  3. ^ Bernan; British Pharmacopoeia Commission (February 2002). British Approved Names 2002. The Stationery Office. p. 157. ISBN 978-0-11-322558-3. Retrieved 17 November 2011.