The settlement is first documented in 1184 as belonging to the powerful abbey of Corbie. The name has the same root as hameau ("hamlet"), a small rural settlement.
Like many places in the region, Le Hamel has experienced the ravages of war through the ages, from the conflicts between the French kings and their English, Burgundian, and Spanish adversaries to the battles of the First World War. It was a pivotal place in the latter conflict as the site of the Battle of Hamel which took place on 4 July 1918 and was a prelude to the summer offensive of 8 August later in the same year.
A park commemorating the 1000+ Australian troops who died in the Battle of Hamel was inaugurated on 4 July 1998, exactly 80 years after the date of the event. The site symbolises the friendship between France and Australia.