leucine dehydrogenase oktamer, Sporosarcina psychrophila
|PDB structures||RCSB PDB PDBe PDBsum|
|Gene Ontology||AmiGO / QuickGO|
- L-leucine + H2O + NAD+ 4-methyl-2-oxopentanoate + NH3 + NADH + H+
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-leucine:NAD+ oxidoreductase (deaminating). Other names in common use include L-leucine dehydrogenase, L-leucine:NAD+ oxidoreductase, deaminating, and LeuDH. This enzyme participates in valine, leucine and isoleucine degradation and valine, leucine and isoleucine biosynthesis.
- Sanwal BD, Zink MW (1961). "L-Leucine dehydrogenase of Bacillus cereus". Arch. Biochem. Biophys. 94: 430–435. doi:10.1016/0003-9861(61)90070-4.
- Zink MW, Sanwal BD (1962). "The distribution and substrate specificity of L-leucine dehydrogenase". Arch. Biochem. Biophys. 99: 72–77. doi:10.1016/0003-9861(62)90245-X.
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