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Levoleucovorin is the enantiomerically active form of Folinic acid.

A study from authors at Georgetown University have shown that there is no safety or efficacy benefit to levoleucovorin.[1]


  1. ^ Kovoor, P. A.; Karim, S. M.; Marshall, J. L. (2009). "Is levoleucovorin an alternative to racemic leucovorin? A literature review". Clinical Colorectal Cancer. 8 (4): 200–6. PMID 19822510. doi:10.3816/CCC.2009.n.034.