Lillian Dyck

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The Honourable
Lillian Eva Quan Dyck
Senator from Saskatchewan
Assumed office
March 24, 2005
Nominated by Paul Martin
Appointed by Adrienne Clarkson
Personal details
Born (1945-08-24) August 24, 1945 (age 72)
North Battleford, Saskatchewan
Political party Senate Liberal
Other political
Independent NDP (2005-2009)
Liberal (2009-2014)
Occupation neuroscientist, university professor

Lillian Eva Quan Dyck (born August 24, 1945) is a Canadian senator from Saskatchewan. She was appointed to the Senate on the recommendation of Prime Minister Paul Martin on March 24, 2005.

Upon appointment, Dyck wished to sit as a New Democratic Party senator, but NDP spokesperson Karl Belanger immediately indicated that the party would not recognize her as a member of the NDP caucus: as the party platform specifically favours abolition of the Senate, it refused to confer legitimacy on the body by accepting Dyck; additionally, Dyck's membership in the NDP was revealed to have lapsed.[1] Under the rules of the Senate, senators are free to designate themselves however they see fit, and Dyck changed her designation to say Independent New Democratic Party.[2] On January 15, 2009, she joined the Liberal Senate caucus.[3][4]

On January 29, 2014, Liberal Party leader Justin Trudeau announced all Liberal Senators, including Dyck, were removed from the Liberal caucus, and would continue sitting as Independents.[5] The Senators refer to themselves as the Senate Liberal Caucus even though they are no longer members of the parliamentary Liberal caucus.[6]

Before being appointed to the Senate, Dyck was a neuroscientist with the University of Saskatchewan, where she was also associate dean. On March 12, 1999, Dyck, who is of Cree and Chinese heritage and was one of the first Aboriginal women in Canada to pursue an academic career in the sciences, was presented with a lifetime achievement award by Indspire. She continues to teach at the university as well as conduct research on a part-time basis.

She is a member of the Gordon First Nation.

In 2014 Dyck accused Conservative MP Rob Clarke, who is also native, of "behaving like a white man" by pushing the Indian Act Amendment and Replacement Act. She later said she recognized the comment could be hurtful.[7]

In 2017 a play based on Dyck's life "Cafe Daughter", written by Kenneth T. Williams, directed by Lisa C. Ravensbergen and featuring Tiffany Ayalik, was staged in Ottawa.[8]


Xu, Haiyun, Haitao Wang, Lixia Zhuang, Bin Yan, Yingxin Yu, Zelan Wei, Yanbo Zhang, Lillian E. Dyck, Steven J. Richardson, Jue He, Xiaokun Li, Jiming Kong and Xin-Min Li. "Demonstration of an anti-oxidative stress mechanism of quetiapine." FEBS Journal. 275:14 (July 2008): 3718-28.

Shao, Zongjun, Lillian E. Dyck, Haitao Wang and Xin-Min Li . "Antipsychotic drugs cause glial cell line-derived neurotrophic factor secretion from C6 glioma cells."Journal of Psychiatry and Neuroscience. 31:1 (January 2006):32-7.

Wang, H., H. Xu, Lillian E. Dyck and X-M Li. "Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis."Journal of Neuroscience Research. 81:4 (15 August 2005): 572-80.

Wei, Z., D. D. Mousseau, J. S. Richardson, Lillian E. Dyck and X-M Li, "Atypical antipsychotics attenuate neurotoxicity of beta-amyloid(25-35) by modulating Bax and Bcl-X(l/s) _expression and localization."Journal of Neuroscience Research. 74:6 (15 December 2003) : 942-7.

Dyck, Lillian E. "Dare to be brave: stand up for yourself." In : Women in the Canadian academic tundra: challenging the chill. (eds.) Elena Hannah, Linda Paul, Swani Vethamany-Globus. (Montreal : McGill-Queen's University Press; c2002) : 47-50.

Dyck, Lillian E. and B. A. Davis. "Inibition of rat liver microsomal CYP1A2 and CYP2B1 activity by N-(2-heptyl)-N-methyl-propargylamine and by N-(2-heptyl)-propargylamine."Drug Metabolism and Disposition. 29:8 (August 2001) :1156-61.

Durden, D.A., Lillian E. Dyck, B. A. Davis, Y.D. Liu and A. A. Boulton. "Metabolism and pharmacokinetics, in the rat, of (R)-N-(2-Heptyl)Methyl-propargylamine (R-2HMP), a new potent monoamine oxidase inhibitor and antiapoptotic agent." Drug Metabolism and Disposition. 28:2 (February 2000):147-54.

Boulton, A. A., P. H. Yu, B. A. Davis, I. A. Paterson, X.M. Li, A. V. Juorio, D. A. Durden and Lillian E. Dyck. "Aliphatic N-methylpropargylamines: monoamine oxidase-B inhibitors and antiapoptotic drugs." Advances in Pharmacology. 42 (1998) : 308-11.

Dyck, Lillian E.. "Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots."Alcoholism, Clinical and Experimental Research. 19:2 (April 1995): 420-6.

Dyck, Lillian E. "An Analysis of Western, Feminist and Aboriginal Science Using he Medicine Wheel of the Plains Indians," Native Studies Review, vol. 11, no. 2,(1996): 89-102.

Dyck, Lillian E., D. A. Durden and A. A. Boulton. "Conjugation of phenylacetic acid and m- and p-hydroxyphenylacetic acids in the rat striatum." Life Sciences. 53:11 (1993): 901-9.

Dyck, Lillian E., D. A. Durden and A. A. Boulton. "Effects of monoamine oxidase inhibitors on the acid metabolites of some trace amines and of dopamine in the rat striatum."Biochemical Pharmacology. 45 (24 March 1993):1317-22.

Dyck, Lillian E."Absence of the atypical mitochondrial aldehyde dehydrogenase (ALDH2) isozyme in Saskatchewan Cree Indians."Human Heredity. 43:2 (March/April 1993): 116-20.

Dyck, Lillian E. and A. A. Boulton. "Reversible amine -- selective effects of acute and chronic brofaromine treatment in the rat." Life Sciences. 51:1 (1992):59-66.

Dyck, Lillian E.."The University of Saskatchewan: a portrait." Women's Education. 9:2 (1991) :23.

Yu, P. H., C. Y. Fang and Lillian E. Dyck. "Cutaneous vasomotor sensitivity to ethanol and acetaldehyde: subtypes of alcohol-flushing response among Chinese." Alcoholism, Clinical and Experimental Research.14:6 (December 1990) : 932-6.

Dyck, Lillian E.. "Isoenzymes of aldehyde dehydrogenase in human lymphocytes." Alcoholism, Clinical and Experimental Research. 14:4 (August 1990) :534-8.

Dyck, Lillian E. and A. A. Boulton. "Effects of antidepressant drugs on inositol phospholipid hydrolysis in rat cerebral cortical slices." Neurochemical Research. 14:11 (November 1989) :1047-52.

Dyck, Lillian E. and A. A. Boulton. "Effects of beta-phenylethylamine on polyphosphoinositide turnover in rat cerebral cortex." Neurochemical Research. 14:1(January 1989):63-7.

Dyck, Lillian E.. "Release of some endogenous trace amines from rat striatal slices in the presence and absence of a monoamine oxidase inhibitor." Life Sciences. 44:17 (1989) : 1149-56.

Dyck, Lillian E. "Inhibition of polyphosphoinositide turnover in rat cerebral cortex by clonidine. "Life Sciences. 45:11(1989):993-9.

Dewar, K. M., Lillian E. Dyck, D. A. Durden and A. A. Boulton. "Effect of deuterium substitution on the penetration of beta-phenylethylhydrazine into the rat brain."Biochemical Pharmacology. 37:13 (1 July 1988): 2703-4.

Dyck, Lillian E., A. V. Juorio, D. A. Durden and A. A. Boulton. Effect of chronic deuterated and non-deuterated phenelzine on rat brain monoamines and monoamine oxidase. Naunyn-Schmiedeberg’s Archives of Pharmacology. 337:3 (March 1988) : 279-83.

Dewar, K. M., Lillian E. Dyck, D. A. Durden and A. A. Boulton. "Involvement of brain trace amines in the behavioural effects of phenelzine."Neurochemical Research. 13:2 (February 1988):113-9.

Dyck, Lillian E., "Release of Some Endogenous Trace Amines From Rat Striatal Slices in the Presence and Absence of a Monoamine Oxidase Inhibitor." Trace Amines: Comparative and Clinical Neurobiology, eds. Alan A. Boulon, A.V. Juorio, R.G.H. Downer. (The Humana Press Inc.,1988): 223-237.

Dyck, Lillian E. "Effect of decarboxylase inhibitors on brain p-tyrosine levels."Biochemical Pharmacology. 36:8 (April 1987): 1373-6.

Dyck, Lillian E. "Effect of monofluoromethyldopa (MFMD) on trace amine levels. "Life Sciences. 40:6 (9 February 1987):571-5.

Dyck, Lillian E. and K. M. Dewar. "Inhibition of aromatic L-amino acid decarboxylase and tyrosine aminotransferase by the monoamine oxidase inhibitor phenelzine." Journal of Neurochemistry. 46:6 (June 1986):1899-903.

Dyck Lillian E. and A. A. Boulton. "Effect of deuterium substitution on the disposition of intraperitoneal tryptamine." Biochemical Pharmacology. 35:17 (1 September 1986): 2893-6.

Dyck, Lillian E., D. A. Durden and A. A. Boulton. "Effects of deuterium substitution on the catabolism of beta-phenylethylamine: an in vivo study." Journal of Neurochemistry. 46:2 (February 1986): 399-404.

Dyck, Lillian E. "Are North American Indians Biochemically More Susceptible o he Effects of Alcohol?" Native Studies Review vol. 2 : no. 2 (1986): 85-95.

Dewar, K. M., Lillian E. Dyck, D. A. Durden and A. A. Boulton. "Changes in brain catecholamine levels following DL-dopa are not potentiated by deuterium substitution."Progress in Neuro-psychopharmacology & Biological Psychiatry. 9:5 (1985): 675-80.

Dyck, Lillian E., D. A. Durden and A. A. Boulton. "Formation of beta-phenylethylamine from the antidepressant, beta-phenylethylhydrazine."Biochemical Pharmacology. 34:1 (1 June 1985): 1925-9.

Dyck, Lillian E.."Tryptamine transport in rat brain slices: a comparison with 5-hydroxytryptamine." Neurochemical Research. 9:95 (May 1984) :617-28.

Dyck, Lillian E."The behavioural effects of phenelzine and phenylethylamine may be due to amine release."Brain Research Bulletin. 12:1 (January 1984): 23-8.

Dyck, Lillain E., D. A. Durden, P. H. Yu, B. A. Davis and A. A. Boulton. "Potentiation of the biochemical effects of beta-phenylethylhydrazine by deuterium substitution."Biochemical Pharmacology. 32:9 (1 May 1983):1519-22.

Dyck, Lillian E.. "Release of monoamines from striatal slices by phenelzine and beta-phenylethylamine." Progress in Neuro-psychopharmacology & Biological Psychiatry. 7:4 (1983) :797-800.

Dyck, Lillian E., C. R. Yang and A. A. Boulton. "The biosynthesis of p-tyramine, m-tyramine, and beta-phenylethylamine by rat striatal slices." Journal of Neuroscience Research.10:2 (1983): 211-20.

Dourish, C. T., K. M. Dewar, Lillian E. Dyck and A. A. Boulton. "Potentiation of the behavioural effects of the antidepressant phenelzine by deuterium substitution." Psychopharmacology. 81:2 (1983):122-5.

Dyck, Lillian E. and C. W. Kazakoff. "Acceleration of the biosynthesis of rat striatal dopamine by incubation and by administration of gamma-butyrolactone." Journal of Neuroscience Research. 8:1 (1982): 57-65.

Dyck, Lillian E, C. W. Kazakoff and C. T. Dourish. "The role of catecholamines, 5-hydroxytryptamine and m-tyramine in the behavioural effects of m-tyrosine in the rat." European Journal of Pharmacology. 84:3 (22 October 1982):139-49.

Dyck, L. E., A. V. Juorio and A. A. Boulton. "The in vitro release of endogenous m-tyramine, p-tyramine and dopamine from rat striatum." Neurochemical Research. 7:6 (June 1982) :705-16.

Dourish, C. T., B. A. Davis, L. E. Dyck, R. S. Jones and A. A. Boulton. "Alterations in trace amine and trace acid concentrations in isolated aggressive mice." Pharmacology Biochemistry and Behavior. 17:6 (4 December 1982) :1291-4.

Dourish, C.T., A. A. Boulton and Lillian E. Dyck. "Biphasic behavioural stimulation induced by a monoamine oxidase-inhibiting antidepressant." Progress in Neuro-psychopharmacology & Biological Psychiatry. 6:4 (1982) :383-8.

Dyck, Lillian E., C. W. Kazakoff and C. T. Dourish. "Behavioural and neurochemical effects of meta-tyrosine in the rat." Progress in Neuro-psychopharmacology & Biological Psychiatry. 6:4 (1982): 389-94.

Dyck, Lillian E.."Release of radiolabeled dopamine, p-tyramine, and m-tyramine from rat striatal slices by some aminotetralins." Neurochemical Research. 6:4 (April 1981) : 365-75.

Dyck, Lillian E.. "Methylphenidate-like stimulants in vitro release [3H]tyramines but not [14C]dopamine."European Journal of Pharmacology. 69:3 (29 January 1981):371-4.

Dyck, Lillian E. An in vitro study of the uptake and release of m- and p-tyramine .Thesis (Ph.D.) -- University of Saskatchewan;1981.

Dyck, Lillian E., A. A. Boulton and R. S. Jones. "A comparison of the effects of methylphenidate and amphetamine on the simultaneous release of radiolabelled dopamine and p- or m-tyramine from rat striatal slices." European Journal of Pharmacology. 68:1 (1980) : 33-40.

Petrali, E.H., A. A. Boulton and Lillian E. Dyck. "Uptake of para-tyramine and meta-tyramine into slices of the caudate nucleus and hypothalamus of the rat." Neurochemical Research. 4:5 (October 1979): 633-42.

Dyck, Lillian E.."Uptake and release of meta-tyramine, para-tyramine, and dopamine in rat striatal slices." Neurochemical Research. 3:6 (December 1978):775-91.

Wu, P. H. and Lillian E. Dyck. "Microassay for the estimation of monoamine oxidase activity." Analytical Biochemistry. 72 (7 May 1976): 637-42.

Dyck, Lillian E. and A. A. Boulton. "The effect of some drugs on the urinary excretion of some aryl alkyl amines in the rat." Research Communications in Chemical Pathology and Pharmacology. 11:1 (May 1975) :73-7.

Boulton, A. A. and Lillian E. Dyck. "Biosynthesis and excretion of meta and para tyramine in the rat." Life Sciences. 14:12 (16 June 1974): 2497-506.

Boulton, A. A., Lillian E. Dyck and D. A. Durden. "Hydroxylation of beta-phenylethylamine in the rat." Life Sciences. 15: 9 (1 November 1974):1673-83.

Dyck, Lillian E.. Identification and metabolism of certain biogenic amines in brain. MS Thesis. University of Saskatchewan. 1970.


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