Linear and whorled nevoid hypermelanosis

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Linear and whorled nevoid hypermelanosis (also known as "Linear nevoid hyperpigmentation," "Progressive cribriform and zosteriform hyperpigmentation," "Reticulate and zosteriform hyperpigmentation," "Reticulate hyperpigmentation of Iijima and Naito and Uyeno," "Zebra-like hyperpigmentation in whorls and streaks," and "Zebra-line hyperpigmentation"[1]) is a disorder of pigmentation that develops within a few weeks of birth and progresses for one to two years before stabilizing.[2]:549 There is linear and whorled hyperpigmentation following the lines of Blaschko without preceding bullae or verrucous lesions.[2]:549 It is important to exclude other pigmentary disorders following the Blaschko lines before making a diagnosis of linear and whorled nevoid hypermelanosis.The differential diagnoses include incontinentia pigmenti, linear epidermal nevus, hypomelanosis of Ito and Goltz syndrome. Recently, a case of linear and whorled nevoid hypermelanosis was reported in a Malaysian Chinese girl.[3]

See also[edit]


  1. ^ Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ^ a b James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  3. ^ Yap FBB. Linear and whorled nevoid hypermelanosis in a Malysian Chinese girl. Egyptian Dermatology Online Journal 2008; 4(2).