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Lipiduria or lipuria is the presence of lipids in the urine. Lipiduria is most frequently observed in nephrotic syndrome where it is passed as lipoproteins along with other proteins.[1][2] It has also been reported as a sign following fat embolism.[3]

When lipiduria occurs, epithelial cells or macrophages contain endogenous fats. When filled with numerous fat droplets, such cells are called oval fat bodies. Oval fat bodies exhibit a "Maltese cross" configuration under polarized light microscopy.[4] This Maltese cross is because of its liquid-crystalline structure giving it a double refraction (birefringence).

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  1. ^ Klahr S, Tripathy K, Bolanos O (1967). "Qualitative and Quantitative Analysis of Urinary Lipids in the Nephrotic Syndrome". J. Clin. Invest. 46 (9): 1475–81. doi:10.1172/JCI105639. PMC 292893Freely accessible. PMID 6036540. 
  2. ^
  3. ^ Findlay J, DeMajo W (1 January 1984). "Cerebral fat embolism" (Image & PDF). Canadian Medical Association journal. 131 (7): 755–7. PMC 1483580Freely accessible. PMID 6478364. 
  4. ^