Lipophobicity, also sometimes called lipophobia (from the Greek λιποφοβία from λίπος lipos "fat" and φόβος phobos "fear"), is a chemical property of chemical compounds which means "fat rejection", literally "fear of fat". Lipophobic compounds are those not soluble in lipids or other non-polar solvents. From the other point of view, they do not absorb fats.
The most common lipophobic substance is water.
A lipophobic coating is used on the touchscreens of Apple's iPhones since the 3GS, their iPads, Nokia's N9 and Lumia devices, the HTC HD2, Hero, and Flyer  and many other phones to repel fingerprint oil, which aids in preventing and cleaning fingerprint marks. Most "Oleophobic" coatings used on mobile devices are fluoropolymer-based solids (similar to Teflon, which was used on the HTC Hero) and are both lipophobic and hydrophobic. In addition to being lipophobic or oleophobic, perfluoropolyether coatings impart exceptional lubricity to touch screens and give them a "slick feel" that eases their use. Use of isopropyl alcohol to clean the screen can damage or remove the coating.
Several products exist to restore or add a lipophobic coating to devices lacking one.
- Nye, Bill (2009-06-24). "Giz Bill Nye Explains: The iPhone 3GS's Oleophobic Screen". Gizmodo. Retrieved 2014-09-11.
- "Apple iPad Specs Page". Apple. 2010-01-27.
- Taylor, Alun (2011-06-09). "HTC Flyer 7in Android Tablet review". The Register. Retrieved 2014-09-11.
- "HTC Hero Specifications". GSMArena. Retrieved 2014-09-11.
- "Fluorosilanes". Cytonix. 2015-01-12.
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