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Lipozene is a brand name dietary supplement sold by Obesity Research Institute, LLC. The primary ingredient in Lipozene is glucomannan.


Lipozene contains a single ingredient, glucomannan, a water-soluble, fermentable dietary fiber extracted from the tuber or root of the elephant yam, also known as Konjac (Amorphophallus konjac or A. rivieri).[1]


Clinical trials examining the use of glucomannan for weight loss have produced mixed results.[2][1] A 2014 systematic review and meta-analysis of clinical trials failed to show that glucomannan supplementation generated statistically significant weight loss.[3] Obesity Research Foundation, LLC was fined $1.5 million by the Federal Trade Commission in 2005 for misleading statements about weight-loss results from a similar glucomannan-containing product.[4]

Adverse events[edit]

Adverse events include abdominal discomfort, diarrhea, and constipation.[3]


  1. ^ a b Keithley,J., Swanson, B., Mikolaitis, M., DeMeo, J., Zeller, L., Fogg, Adamji, J. 2013. Safety and Efficacy of Glucomannan for Weight Loss in Overweight and Moderately Obese Adults. J Obes. 2013; 2013: 610908
  2. ^ Salas-Salvadó J, Farrés X, Luque X, Narejos S, Borrell M, Basora J, Anguera A, Torres F, Bulló M, Balanza R (2008). "Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial". Br J Nutr. 99 (6): 1380–7. doi:10.1017/S0007114507868528. PMID 18031592.
  3. ^ a b Onakpoya I, Posadzki P, Ernst E (February 2014). "The efficacy of glucomannan supplementation in overweight and obesity: a systematic review and meta-analysis of randomized clinical trials". Journal of the American College of Nutrition. 33 (1): 70–8. doi:10.1080/07315724.2014.870013. PMID 24533610.
  4. ^ "FTC Settles Claims with Marketers of FiberThin and Propolene". Federal Trade Commission (Press release). June 20, 2005. Retrieved November 23, 2017.

External links[edit]