Lewis is the author of six books of poetry and is the director of the creative writing program at Oklahoma State University. In 2011, she received an Individual Artist's Fellowship from the National Endowment for the Arts. She is the Editor in Chief and Poetry Editor of the literary magazine housed at Oklahoma State University, the Cimarron Review. Her first book, The Unbeliever, was published as winner of the Brittingham Prize in 1994. Silent Treatment, winner of the National Poetry Series, appeared from Viking/Penguin in 1998. New Issues Press published Vivisect in 2010, and Burned House with Swimming Pool, appeared as winner of the American Poetry Journal Prize in 2011. In 2016, The Body Double appeared from Georgetown Review Press. The poet Ada Limon calls Lewis’ poems “acutely honest, bristling with beauty, and terribly real. She goes on to say, “calling out from the rural horse pastures and the blackness of the mind's night, The Body Double is, at once, a tribute to the world's roughness and bowing down to its mysterious power.”In 2017, she received the Tenth Gate Prize, a prize awarded each year to an exceptional manuscript by a mid-career poet with at least two previous books, from the Word Works.