The characters listed in this section are those whose portrayer has appeared in the opening credits. They are listed according to the order in the opening credits.
Hobson, who grew up in the state of Indiana, lived and worked in Chicago as a stockbroker until his wife Marsha left him. After this dramatic event, Gary began receiving The Paper, and subsequently left his job. As he kept encountering more and more opportunities to help people and prevent tragedies using The Paper, he proved himself to be a person of high integrity and upstanding morals. Gary had difficulty finding another love interest, and at the conclusion of the series still remained single.
Blind since the age of 16 months after contracting meningitis, she was formerly a receptionist at the stock brokerage firm Hobson formerly worked at. She too left the brokerage firm, ultimately helping Gary Hobson manage McGinty's Bar later in the series. During the first season, Gary uses horse-track winnings to help her purchase a guide dog named Spike, who remained with her until the show's end. Similar to Gary, Marissa was never married during the series.