List of Major League Baseball career slugging percentage leaders

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This is a list of Major League Baseball (MLB) players with a career .500 slugging percentage (SLG). Babe Ruth holds the MLB record with .6897.

Listed are all MLB players with .500 slugging percentage with at least 3,000 plate appearances. Players in bold face are active as of the end of June 8, 2015 (including free agents).