U.S. PresidentDonald Trump ordered an airstrike against the Syrian government in response to the Khan Shaykhun chemical attack on 4 April. The United States gave Syria's ally, Russia, advance warning of the airstrike, allowing the government to move away most planes from the airbase ahead of time. Nine to twenty aircraft were destroyed and seven to nine soldiers were killed, including a general.
U.S. aircraft conducted airstrikes against vehicles, including a tank and bulldozer belonging to pro-government militias that were setting up fighting positions within the Al-Tanf deconfliction zone. Two tanks were destroyed and eight soldiers were killed.
U.S. aircraft conducted airstrikes on over 60 troops, a tank, artillery, antiaircraft weapons, and armed technical vehicles from pro-government forces that had entered the Al-Tanf deconfliction zone. The attack killed an unknown number of men and destroyed two artillery pieces, an anti-aircraft gun, and a tank.
The U.S.-led Coalition forces conducted air and artillery strikes to destroy pro-government forces that were advancing against a SDF headquarters, which was housing U.S.-led Coalition service members at the time. Over 100 pro-government troops were reported to have been killed and hundreds more were injured. In addition, Syrian state media announced that 10 Russian mercenaries had been killed.
A U.S. MQ-9 Reaper drone destroys a T-72 tank of pro-government forces in an air strike near the Al Tabiyeh gas field. The tank itself was not firing on the SDF and the coalition, but other elements in the formation were.
The Syrian Army, along with what is believed to be Iranian-backed militias, captured villages east of the Euphrates river near the city of Deir ez-Zor that were under the control of Kurdish-led forces in a rare clash with the Syrian Democratic Forces. Later that same day, the territory was recaptured by U.S.-backed proxy forces in a counter-attack spearheaded by the YPG with help from U.S. coalition jets. U.S. coalition jets hit the attacking forces consisting of the Syrian Army and possibly Iranian militias, according to a Western diplomat and a source in the SDF.
The Deir ez-Zor air raid was a series of 37 U.S.-led Coalition airstrikes near the Deir ez-Zor Airport in eastern Syria on 17 September 2016 that killed between 90 and 106 Syrian Army soldiers and wounded 110 more. The United States said that the intended target was Islamic State of Iraq and the Levant militants and that the attack on Syrian soldiers was due to a misidentification of ground forces while the Syrian and Russian governments claimed that it was an intentional attack against Syrian troops. The attack prompted Russia to call an emergency United Nations Security Council meeting. Later, the Syrian government called off a ceasefire that had been the result of months of intense diplomatic efforts by the U.S. and Russian governments.