1886 - Seven police officers and four civilians are killed by a bomb thrown in Chicago's Haymarket Square as the police attempted to break up a rally. An unknown number of others were killed as police and demonstrators exchanged gunfire following the bomb blast. This and subsequent events are known as the Haymarket affair.
1890 - David Hennessy, Police Chief of New Orleans is shot, allegedly by the Mafia.
1905 - Former Idaho governor Frank Steunenberg was assassinated with a bomb outside his home in Caldwell, Idaho. The assassin, Harry Orchard, was quickly apprehended and said he had been hired by the Western Federation of Miners to assassinate Steunberg as revenge for breaking up miners' strikes. However, the labor leaders charged in this conspiracy were acquitted.
1912 - Former US President Theodore Roosevelt, who was campaigning to return to office, is shot by John Flammang Schrank weeks before the 1912 presidential election. Roosevelt is seriously injured but survives.
1915 - RMS Lusitania is torpedoed and sunk by German submarine U-20 off Ireland. 128 US nationals killed.
1916 - 10 died and 40 were injured in the Preparedness Day Bombing in San Francisco. Two labor leaders, Warren K. Billings and Thomas Mooney were convicted, but pardoned later due to lack of evidence. The actual bombers' identity remains unknown.
1920 - The Wall Street bombing kill 28 and seriously injures 143. Galleanist anarchists were suspected, but no one was ever caught.
1921 - In the Tulsa race riot, reports claimed that whites in airplanes dropped dynamite onto an area called the Black Wall Street. Around 39-300 people were killed with more than 1,100 homes and businesses destroyed in the riot.
1979 - U.S. embassy burning in Islamabad - embassy was attacked by mob because a radio report mistakenly blamed the US for the seizure of the Grand Mosque in Mecca; actions that were carried out by a radical Islamic faction Grand Mosque Seizure. Two Americans and two Pakistani members of the embassy staff were killed.
1984 - Twenty-two people were killed (two of them American) and seventy were wounded when a van loaded with four hundred pounds of explosives exploded in front of the U.S. Embassy annex in Awkar, Lebanon. Islamic Jihad (code name of Hezbollah) claimed responsibility for the bombing in a call to the media.
1985 - August 9 - The car bomb planted at Rhein-Main Air Base explodes, killing two and wounding eleven.
1985 - October 7 - Achille Lauro hijacking, Leon Klinghoffer, a wheel-chair bound American is killed by Palestinian militants.
1985 - October 11 - Alex Odeh assassinated in a bombing as he opened the door of his office at 1905 East 17th Street, Santa Ana, California. Odeh was west-coast regional director of the American-Arab Anti-Discrimination Committee (ADC). The FBI charged Robert Manning, a member of the JDL, with the murder. Manning flees to Israel, but is later extradited for a different murder, tried and sentenced to 30 years. Odeh's murder remains technically unsolved.
1985 - November 25 - A car bomb explodes outside of the Post Exchange complex in Frankfurt, Germany, wounding 34
1986 - April 6 - A Berlin discotheque bombing kills a Turkish woman and 2 US servicemen and injures 230 people, including more than 50 American servicemen.
1987 - A car bomb explodes outside the back gate of the U.S. Embassy in Rome and mortars are fired at the compound from across the street. One passerby is injured in the attacks.
1988 - April 14 - At 8 p.m., a car bomb explodes in front of the USO Club in Naples, Italy. Five people die and fifteen are injured, including four U.S. servicemen who are injured and US Navy Petty Officer Angela Santos, 21, are killed. Junzo Okudaira, a Japanese Red Army (JRA) member, was indicted in the United States on April 9, 1993 for the Naples bombing. Okudaira is also a suspect in the June 1987 car bombing and mortar attack against the U.S. Embassy in Rome.
1988 - December 21 - Pan Am Flight 103, outbound from London for New York with 259 people aboard, is destroyed by a bomb on December 21, 1988 while over Lockerbie, Scotland. All aboard the aircraft are killed as were eleven persons on the ground.
1988 - 1990 - Marine Col. Rich Higgins kidnapped, tortured and murdered by Hezbollah terrorists.
2009 - Thirteen people, mostly U.S. military personnel, are killed and more than 30 others wounded at Fort Hood, Texas, in a shooting rampage by disgruntled Army psychiatrist Nidal Malik Hasan, who during his trial claimed to be waging an Islamic jihad against the United States.
2015 - 2015 San Bernardino attack in San Bernardino, California, married couple Rizwan Farook and Tashfeen Malik enter at the Inland Regional Center, a government-funded not-for-profit public benefit corporation that provides services and programs to people with developmental disabilities and their families in California's San Bernardino and Riverside Counties. They shot and killed 14 people and injured 24 others, including 2 officers.
2016 - 2016 Orlando nightclub shooting in Orlando, Florida, a lone gunman, claiming Islamic terrorist ties, entered an LGBT nightclub (Pulse Nightclub on Latin Night), killed 49 patrons, injured at least 53 others, and took hostages during a three to four hour massacre during the early morning hours of June 12, 2016. The gunman was shot and killed during shoot out with police officers at about 5:15am.