1886 - May 4 - Seven police officers and four civilians were killed by a bomb thrown in Chicago's Haymarket Square as the police attempted to break up a rally. An unknown number of others were killed as police and demonstrators exchanged gunfire following the bomb blast. This and subsequent events are known as the Haymarket affair.
1905 - December 30 - Former Idaho governor Frank Steunenberg was assassinated by a bomb outside his home in Caldwell, Idaho. The assassin, Harry Orchard, was quickly apprehended and claimed he had been hired by the Western Federation of Miners to assassinate Steunberg in revenge for his breaking up miners' strikes. The labor leaders charged in this conspiracy were acquitted, though.
1912 - October 16 - Former US President Theodore Roosevelt, who was campaigning to return to office, was shot by John Flammang Schrank weeks before the 1912 presidential election. Roosevelt was seriously injured but survived.
1916 - July 22 - 10 died and 40 were injured in the Preparedness Day Bombing in San Francisco. Two labor leaders, Warren K. Billings and Thomas Mooney were convicted, but were later pardoned owing to lack of evidence. The identity of the bombers' remains unknown.
1917 - November 24 - A bomb exploded in a Milwaukee police station, killing nine officers and a civilian. Anarchists were suspected.
1920 - September 16 - The Wall Street bombing killed 28 and seriously injured 143. Galleanist anarchists were suspected, but no one was ever caught.
1921 - May 31—June 1 - In the Tulsa race riot, reports claimed that whites in airplanes dropped dynamite onto an area called the Black Wall Street. Perhaps as many as 300 people were believed killed, with more than 1,100 homes and businesses destroyed in the riot.
1933 - October 10 - 1933 United Airlines Boeing 247 mid-air explosion A Boeing 247 was destroyed in mid-flight over Indiana by a nitroglycerin bomb. All seven people aboard were killed. This incident was the first proven case of air sabotage in the history of aviation. The identity of the perpetrator and the motive for the attack are unknown.
1937 - October 13 - Theodore Marriner, Consul General to Syria, was assassinated in Beirut.
1975 – December 29 – A bomb goes off near a luggage carousel at LaGuardia Airport in New York City, killing 11. Croatian nationalists who had planted a bomb months earlier at Grand Central Terminal were suspected, but no groups claimed responsibility, and no suspects have ever been named. It has been theorized that the bomb was meant to go off in the morning, instead of the evening, which would likely have led to fewer, if any, deaths, and that might be why those who planted it declined to take credit.
1979 - November 21 - The U.S. embassy Islamabad was attacked and burned by a mob after a radio report mistakenly blamed the US for the seizure of the Grand Mosque in Mecca. This seizure was actually carried out by a radical Islamic faction Grand Mosque Seizure. Two Americans and two Pakistani members of the embassy staff were killed.
1984 - September 20 - Twenty-two people were killed (two of them American) and seventy wounded when a van loaded with four hundred pounds of explosives was detonated in front of the U.S. Embassy annex in Awkar, Lebanon. Islamic Jihad (a code name of Hezbollah) claimed responsibility for the bombing in a call to the media.
1985 - October 7 - The Achille Lauro hijacking; Leon Klinghoffer, a wheel-chair bound American, was killed by Palestinian militants.
1985 - October 11 - Alex Odeh was assassinated in a bombing as he opened the door of his office at 1905 East 17th Street, Santa Ana, California. Odeh was west-coast regional director of the American-Arab Anti-Discrimination Committee (ADC). The FBI charged Robert Manning, a member of the JDL, with the murder. Manning fled to Israel, but was later extradited for a different murder, tried and sentenced to 30 years. Odeh's murder remains technically unsolved.
1985 - November 25 - A car bomb exploded outside the Post Exchange complex in Frankfurt, Germany, wounding 34.
1986 - April 6 - A Berlin discotheque bombing killed a Turkish woman and 2 US servicemen, and injured 230 people including more than 50 American servicemen.
1987 - June 9 - A car bomb exploded outside the back gate of the U.S. Embassy in Rome and mortars were fired at the compound from across the street. One passerby was injured in the attacks.
1988 - April 14 - At 8 p.m., a car bomb exploded in front of the USO Club in Naples, Italy. Five people died and fifteen were injured, including four U.S. servicemen. US Navy Petty Officer Angela Santos, 21, was killed. Junzo Okudaira, a Japanese Red Army (JRA) member, was indicted in the United States on April 9, 1993 for the Naples bombing. Okudaira was also a suspect in the June 1987 car bombing and mortar attack against the U.S. Embassy in Rome.
1988 - December 21 - Pan Am Flight 103, outbound from London for New York with 259 people aboard, was destroyed by a bomb on December 21, 1988 while over Lockerbie, Scotland. All aboard the aircraft were killed, as were eleven persons on the ground.
1988 - 1990 - Marine Col. "Rich" Higgins was kidnapped, tortured and murdered by Hezbollah terrorists.
1990 - November 5 - Meir Kahane, Brooklyn-born Jewish Defense League founder and later an Israeli politician, was killed in New York by a gunman, El Sayyid Nosair, who was later convicted of the assassination following a federal anti-terrorism conspiracy investigation.
2009 - November 5 - Thirteen people, mostly U.S. military personnel, were killed and more than 30 others wounded at Fort Hood, Texas, in a shooting rampage by disgruntled Army psychiatrist Nidal Malik Hasan. During his trial, Hasan claimed to be waging an Islamic jihad against the United States.
2015 - December 2 - In an attack in San Bernardino, California, married couple Rizwan Farook and Tashfeen Malik entered the Inland Regional Center, a government-funded not-for-profit public benefit corporation that provides services and programs to people with developmental disabilities and their families in California's San Bernardino and Riverside Counties. They shot and killed 14 people and injured 24 others, including 2 officers.
2016 - June 12 - In the Orlando nightclub shooting a lone gunman entered Pulse Nightclub (an LGBT club) on Latin Night. He killed 49 patrons, injured at least 53 others, and took hostages during a three—four hour massacre during the early hours The gunman was shot and killed at c.5:15am, during a shoot out with police officers.
2017 - January 7, a US consulate officer name Christopher Ashcraft is shot in the chest at a mall in Guadalajara, Mexico but he survives, the shooter was an Indian man with U.S citizenship name Zafar Zia.The motives remain unknown.