Lodhran District (Urdu: ضِلع لودهراں), is a district in the Punjab, Pakistan - the city of Lodhran is the capital of the district. It is located on the northern side of River Sutlej. It is bounded to the north by the districts of Multan, Khanewal and Vehari, to the south by Bahawalpur, to the east lie the districts of Vehari and Bahawalpur; while district Multan lies on the western side. It has the lowest Human Development Index of all districts in Punjab. The district was created in 1991 and is a well-known cotton-growing area.