Wiggers studied architecture at the Aarhus School of Architecture and the Ecole des Beaux Arts in Paris. After a year in London working with the Project Design Partnership (1989), she returned to Copenhagen where she joined Anna Maria Indrio (1990) before joining C. F. Møller Architects where she became a partner in 1997. Wiggers has participated in a wide range of projects including residential housing, commercial buildings, schools, old people's homes, hospitals and museums. They cover both new constructions and the conversion and restoration of older buildings. She has served on many boards and committees, heading the architecture committee for the Danish Ministry of Culture's cultural canon and participating in the Special Building Survey Council for the Cultural Heritage Board since 2003.
- "Lone Wiggers" Archived 2012-12-15 at Archive.today, International Archive of Women in Architecture. Retrieved 24 February 2012.
- "Præsentation af Lone Wiggers" Archived 2016-03-04 at the Wayback Machine, Arkitektskolen Aarhus. (in Danish) Retrieved 24 February 2012.
- "CV'er - Kanonudvalget for Architektur" Archived 2012-05-27 at Archive.today, Kulturministeriet. (in Danish) Retrieved 24 February 2012.