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Loti may refer to:
- Loti, Pakistan, a town and union council
- Pierre Loti, the pseudonym of Louis Marie Julien Viaud, a French writer
- Lesotho loti, the official currency of Lesotho
- LOTI, Internet slang for "laughing on the inside"
- Levels of Technology Integration - The LoTI model for assessing technology integration in schools