Lou Michaels (born September 28, 1935) is a former American football player who was a standout defensive lineman for the University of Kentucky Wildcats from 1955 to 1957. After Kentucky's victory over archrival Tennessee in 1957, Michaels was quoted as saying, "Nothing sucks like a Big Orange." Michaels played professionally for 14 years, 1958–1971, with the Los Angeles Rams, Pittsburgh Steelers, Baltimore Colts and Green Bay Packers of the National Football League (NFL). He also excelled as a placekicker, and was selected to the Pro Bowl after the 1962 and 1963 seasons.
Michaels was inducted into the College Football Hall of Fame in 1992 and into the National Polish American Sports Hall of Fame in 1994. His brother, Walt Michaels, also played in the NFL.