André was born in Saint-Rémy-de-Provence. He was ordained a priest of the Jesuit order and was sent to serve in the Jesuit mission in Canada in 1669. He assisted in the formal ceremony declaring the North West Territory was the territory of the King of France. His first missionary duty was served among the Indians around Lake Huron.
André's ministry in the New World combined a great deal of missionary work as well as a number of years teaching philosophy and Latin. At some time in Canada he compiled an important Algonkin and Ottawa dictionary and a small conversational manual which still exists.