Louis Lapicque

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Louis Lapicque

Louis Édouard Lapicque (1 August 1866 – 6 December 1952) was a French neuroscientist, socialist activist, antidreyfusard and freemason[1] who was very influential in the early 20th century. One of his main contributions was to propose the integrate-and-fire model of the neuron in a seminal article published in 1907.[2] Today, this model of the neuron is still one of the most popular models in computational neuroscience for both cellular and neural networks studies, as well as in mathematical neuroscience because of its simplicity. A review article [3] was published for the centenary of the original Lapicque's 1907 paper - this review also contains an English translation of the original paper.

His wife, Marcelle Lapicque, was also a neurophysiologist.[4] Louis Lapicque "insisted on the importance of his wife as equal co-worker in all his research".[5]

Lapicque's laboratory at the Sorbonne


  • Notice on titles and scientific works of Louis Lapicque (1908)
  • Excitability function of time, chronaxie, its meaning and its measure (1926)
  • Nervous machine (1943)
  • Neuromuscular isochronism and rythmogenic excitability (1947)
  • On reaction times according to races and social conditions (1901)
  • Quantitative research on nervous electrical excitation treated like a polarization (1907)
  • Consciousness as a cellular function (1952)

See also[edit]


  1. ^ in Frédéric Joliot-Curie page 578 by Michel Pinault (Editions Odile Jacob, 2000)
  2. ^ Lapicque L (1907). "Recherches quantitatives sur l'excitation électrique des nerfs traitée comme une polarisation". J. Physiol. Pathol. Gen. 9: 620–635.
  3. ^ Brunel N, Van Rossum MC (2007). "Lapicque's 1907 paper: from frogs to integrate-and-fire". Biol. Cybern. 97 (5–6): 337–339. doi:10.1007/s00422-007-0190-0. PMID 17968583.
  4. ^ Ogilvie, Marilyn Bailey; Harvey, Joy Dorothy (2000). "Lapicque, Marcelle (de Heredia) (1873–ca.1962)". The Biographical Dictionary of Women in Science: L-Z. Taylor & Francis. pp. 745–746. ISBN 9780415920407.
  5. ^ Lykknes, Annette; Opitz, Donald L.; Van Tiggelen, Brigitte, eds. (2012). "Louis and Marcelle Lapicque". For Better or For Worse? Collaborative Couples in the Sciences. Science Networks Historical Studies. 44. Birkhäuser. pp. 66–67. ISBN 9783034802864..

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