Low-intensity pulsed ultrasound

From Wikipedia, the free encyclopedia
  (Redirected from Low intensity pulsed ultrasound)
Jump to: navigation, search
Low-intensity pulsed ultrasound

Low-intensity pulsed ultrasound (LIPUS) is a medical technology, generally using 1.5 MHz frequency pulses, with a pulse width of 200 μs, repeated at 1 kHz, at a spatial average and temporal average intensity of 30 mW/cm2.[1] As of 2009 research for the use of LIPUS to treat soft tissue injuries were in the early stages.[1] As of 2012 it was being studied for dental problems.[2]

Medical uses[edit]

A 2017 review recommended against its use to speed healing of bone fractures.[3] Evidence as of 2014 was insufficient to justify its use to prevent non healing of bone fractures.[4] Tentative evidence supports better healing with the use of the system in long bones that have no health after three months.[5]


Starting around the 1950s this technology was being used as a form of physical therapy for ailments such as tendinitis.[6]


  1. ^ a b Khanna, A; Nelmes, RT; Gougoulias, N; Maffulli, N; Gray, J (2009). "The effects of LIPUS on soft-tissue healing: a review of literature.". British medical bulletin. 89: 169–82. PMID 19011263. 
  2. ^ Rego, E. B. (2012). "Current Status of Low Intensity Pulsed Ultrasound for Dental Purposes". The Open Dentistry Journal. 6: 220–5. PMC 3547311Freely accessible. PMID 23341848. doi:10.2174/1874210601206010220. 
  3. ^ Poolman, RW; Agoritsas, T; Siemieniuk, RA; Harris, IA; Schipper, IB; Mollon, B; Smith, M; Albin, A; Nador, S; Sasges, W; Schandelmaier, S; Lytvyn, L; Kuijpers, T; van Beers, LW; Verhofstad, MH; Vandvik, PO (21 February 2017). "Low intensity pulsed ultrasound (LIPUS) for bone healing: a clinical practice guideline.". BMJ (Clinical research ed.). 356: j576. PMID 28228381. 
  4. ^ Griffin, XL; Parsons, N; Costa, ML; Metcalfe, D (23 June 2014). "Ultrasound and shockwave therapy for acute fractures in adults.". The Cochrane database of systematic reviews (6): CD008579. PMID 24956457. 
  5. ^ Higgins, A; Glover, M; Yang, Y; Bayliss, S; Meads, C; Lord, J (October 2014). "EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing: a NICE medical technology guidance.". Applied health economics and health policy. 12 (5): 477–84. PMID 25060830. 
  6. ^ Miller, Douglas; Smith, Nadine; Bailey, Michael; Czarnota, Gregory; Hynynen, Kullervo; Makin, Inder (2012-4). "Overview of Therapeutic Ultrasound Applications and Safety Considerations". Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 31 (4): 623–634. ISSN 0278-4297. PMC 3810427Freely accessible. PMID 22441920.  Check date values in: |date= (help)

External links[edit]