He was praef. ann. and Praefectus of Egypt in 161. When Governor of Alexandria he was slain by the soldiers, as having participated in the rebellion of Avidius Cassius in 175. (Cassius was his son-in-law by marriage to his daughter Volusia Vettia or Volusia Maeciana (c. 135 – aft. 175), the name of his wife being unknown.)
Maecianus was the author of works on trusts (Fideicommissa), on the Judicia publica, and of a collection of the Rhodian laws relating to maritime affairs. His treatise on numerical divisions, weights and measures (Distributio) is extant, with the exception of the concluding portion.