He was private secretary and possibly physician to Rodrigo Borgia, later Alexander VI, and also to Innocent VIII. He rose through the church hierarchy and was made cardinal on 19 February 1500 by Pope Alexander VI. In late 1503 he was considered likely to be elected to the papacy, however, Francesco Todeschini Piccolomini was elected as Pius III. He is buried in the Basilica of Santa Maria del Popolo.
- Gerald Stanley Davies (1916). Renascence: the sculptured tombs of the fifteenth century in Rome. p. 302.
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