Early references to Lukoml in Russian chronicles are dated by 1078, when it was burned by Vladimir Monomakh. In 15-16th centuries it constituted a separate principality. In 1563 it was burned by Russians. In late Russian Empire it was a shtetl of about 1,000 inhabitants with one Orthodox church, one Catholic church, two synagogues, one school and 8 shops. There are remnants of ancient fortifications by the village.