From Wikipedia, the free encyclopedia

Lumbrokinase is a fibrinolytic enzyme[1] present in the earthworm Lumbricus bimastus.[2] It is a clinically approved and proven antithrombotic agent in Asia.[3]


  1. ^ Hu, R. (2004). "Codon optimization, expression, and characterization of recombinant lumbrokinase in goat milk". Protein Expression and Purification. 37 (1): 83–8. doi:10.1016/j.pep.2004.05.018. PMID 15294284.
  2. ^ Ge, T.; Sun, Z.; Fu, S.; Liang, G. (2005). "Cloning of thrombolytic enzyme (lumbrokinase) from earthworm and its expression in the yeast". Protein Expression and Purification. 42 (1): 20–8. doi:10.1016/j.pep.2005.04.005. PMID 15927482.
  3. ^ Kasim, M.; Kiat, A. A.; Rohman, M. S.; Hanifah, Y.; Kiat, H. (2009). "Improved Myocardial Perfusion in Stable Angina Pectoris by Oral Lumbrokinase: A Pilot Study". The Journal of Alternative and Complementary Medicine. 15 (5): 539–44. doi:10.1089/acm.2008.0506. PMID 19416019.