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Lysis can refer to:
- Lysis, the dissolving of cells known more specifically as cytolysis
- Lysis (disease), the reduction of symptoms of a disease
- Lysis (dialogue), a dialogue of Plato about friendship (philia)
- Lysis of Taras, a Greek philosopher
- Lytic cycle, one of the two cycles of viral reproduction, the other being the lysogenic cycle
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