M. Neal Guentzel

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M. Neal "Doc" Guentzel is a doctor working in the fields of infectious diseases, microbes, and bioremediation, as well as a researcher and professor of microbiology at both the University of Texas at San Antonio[1] (UTSA) and the University of Texas Health Science Center at San Antonio. He currently serves as an Associate Dean in the College of Science at UTSA - Downtown Campus.[2]


Guentzel was born in Austin, Texas to Melvin Ace Guentzel and Bessie Guentzel. He attended high school at McCallum High School and The University of Texas at Austin for all his higher education. Guentzel currently resides in San Antonio, Texas, and is an avid fan of the San Antonio Spurs.



Guentzel is a recognized expert on infectious disease, microbiology (with well-known work on Candida albicans and Vibrio cholerae), and bioremediation. He has authored multiple papers in scientific journals and books relating to microbiology. He is a founder and currently co-director of the South Texas Center for Emerging Infectious Diseases,[3] an infectious disease/bioterrorism research facility.

Selected publications[edit]

Guentzel MN (1996). Escherichia, Klebsiella, Enterobacter, Serratia, Citrobacter, and Proteus. In: Baron's Medical Microbiology (Baron S et al., eds.), 4th ed., Univ of Texas Medical Branch. (via NCBI Bookshelf) ISBN 0-9631172-1-1.[4]

Murphey C, Murthy AK, Meier PA, Neal Guentzel M, Zhong G, Arulanandam BP. The protective efficacy of chlamydial protease-like activity factor vaccination is dependent upon CD4+ T cells. Cell Immunol. 2006 Aug;242(2):110-7.

Murthy AK, Cong Y, Murphey C, Guentzel MN, Forsthuber TG, Zhong G, Arulanandam BP. Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun. 2006 Dec;74(12):6722-9.

Cong Y, Jupelli M, Guentzel MN, Zhong G, Murthy AK, Arulanandam BP. Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine. 2007 May 10;25(19):3773-80. Epub 2007 Feb 23.

Beer WH, Johnson RF, Guentzel MN, Lozano J, Henderson GI, Schenker S. Human placental transfer of zinc: normal characteristics and role of ethanol. Alcohol Clin Exp Res. 1992 Feb;16(1):98-105.

Guentzel MN, Cole GT, Pope LM. Animal models for candidiasis. Curr Top Med Mycol. 1985;1:57-116.

Guentzel MN, Guerrero D, DeShambo R. Nature of interaction of different wild type Vibrio cholerae with intestinal mucosa. Scan Electron Microsc. 1983;(Pt 1):263-70.

Guentzel MN. Application of scanning electron microscopy to the study of microorganisms in gastrointestinal pathobiology. Scan Electron Microsc. 1983;(Pt 1):279-92.

Herrera C, Guentzel MN. Mice with persistent gastrointestinal Candida albicans as a model for antifungal therapy. Antimicrob Agents Chemother. 1982 Jan;21(1):51-3.

Guentzel MN, Herrera C. Effects of compromising agents on candidosis in mice with persistent infections initiated in infancy. Infect Immun. 1982 Jan;35(1):222-8.

Field LH, Pope LM, Cole GT, Guentzel MN, Berry LJ. Persistence and spread of Candida albicans after intragastric inoculation of infant mice. Infect Immun. 1981 Feb;31(2):783-91.

Guentzel MN, Amerine D, Guerrero D, Gay TV. Association of Vibrio cholerae mutants with the intestinal mucosa of infant mice. Scan Electron Microsc. 1981;4:115-24.

Dudley DJ, Guentzel MN, Ibarra MJ, Moore BE, Sagik BP. Enumeration of potentially pathogenic bacteria from sewage sludges. Appl Environ Microbiol. 1980 Jan;39(1):118-26.

Pope LM, Cole GT, Guentzel MN, Berry LJ. Systemic and gastrointestinal candidiasis of infant mice after intragastric challenge. Infect Immun. 1979 Aug;25(2):702-7.

Eubanks ER, Guentzel MN, Berry LJ. Evaluation of surface components of Vibrio cholerae as protective immunogens. Infect Immun. 1977 Feb;15(2):533-8.

Guentzel MN, Field LH, Eubanks ER, Berry LJ. Use of fluorescent antibody in studies of immunity to cholera in infant mice. Infect Immun. 1977 Feb;15(2):539-48.

Eubanks ER, Guentzel MN, Berry LJ. Virulence factors involved in the intraperitoneal infection of adult mice with Vibrio cholerae. Infect Immun. 1976 Feb;13(2):457-63.

Guentzel MN, Berry LJ. Motility as a virulence factor for Vibrio cholerae. Infect Immun. 1975 May;11(5):890-7.

Guentzel MN, Berry LJ. Protection of suckling mice from experimental cholera by maternal immunization: comparison of the efficacy of whole-cell, ribosomal-derived, and enterotoxin immunogens. Infect Immun. 1974 Jul;10(1):167-72.