MAPK12

From Wikipedia, the free encyclopedia
Jump to: navigation, search
MAPK12
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MAPK12, ERK3, ERK6, P38GAMMA, PRKM12, SAPK-3, SAPK3, ERK-6, MAPK 12, mitogen-activated protein kinase 12
External IDs MGI: 1353438 HomoloGene: 55705 GeneCards: MAPK12
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002969
NM_001303252

NM_013871

RefSeq (protein)

NP_001290181
NP_002960

NP_038899.1
NP_038899

Location (UCSC) Chr 22: 50.25 – 50.26 Mb Chr 15: 89.13 – 89.14 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Mitogen-activated protein kinase 12 (MAP kinase 12), also known as extracellular signal-regulated kinase 6 (ERK6) or stress-activated protein kinase 3 (SAPK3), is an enzyme that in humans is encoded by the MAPK12 gene.[3]

Function[edit]

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.[3]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.