MAPK4

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MAPK4
Identifiers
Aliases MAPK4, ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK, mitogen-activated protein kinase 4
External IDs MGI: 2444559 HomoloGene: 2058 GeneCards: MAPK4
RNA expression pattern
PBB GE MAPK4 204707 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001292039
NM_001292040
NM_002747

NM_172632

RefSeq (protein)

NP_001278968.1
NP_001278969.1
NP_002738.2

NP_766220.2

Location (UCSC) Chr 18: 50.56 – 50.73 Mb Chr 18: 73.93 – 74.07 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Mitogen-activated protein kinase 4 is an enzyme that in humans is encoded by the MAPK4 gene.[3][4]

Mitogen-activated protein kinase 4 is a member of the mitogen-activated protein kinase family. Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus where it phosphorylates nuclear targets.[4]

The Arabidopsis MAPK4 is important in signalling [5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Li L, Wysk M, Gonzalez FA, Davis RJ (Feb 1994). "Genomic loci of human mitogen-activated protein kinases". Oncogene. 9 (2): 647–9. PMID 8290275. 
  4. ^ a b "Entrez Gene: MAPK4 mitogen-activated protein kinase 4". 
  5. ^ Petersen M, Brodersen P, Naested H, Andreasson E, Lindhart U, Johansen B, Nielsen HB, Lacy M, Austin MJ, Parker JE, Sharma SB, Klessig DF, Martienssen R, Mattsson O, Jensen AB & Mundy J (2000). "Arabidopsis MAP Kinase 4 Negatively Regulates Systemic Acquired Resistance". Cell. 103 (7): 1111–1120. doi:10.1016/S0092-8674(00)00213-0. PMID 11163186. 

External links[edit]

Further reading[edit]