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MAP/microtubule affinity-regulating kinase 3
Protein MARK3 PDB 1ul7.png
PDB rendering based on 1ul7.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MARK3 ; CTAK1; KP78; PAR1A; Par-1a
External IDs OMIM602678 MGI1341865 HomoloGene55653 IUPHAR: 2099 ChEMBL: 5600 GeneCards: MARK3 Gene
EC number
Species Human Mouse
Entrez 4140 17169
Ensembl ENSG00000075413 ENSMUSG00000007411
UniProt P27448 Q03141
RefSeq (mRNA) NM_001128918 NM_021516
RefSeq (protein) NP_001122390 NP_067491
Location (UCSC) Chr 14:
103.39 – 103.5 Mb
Chr 12:
111.57 – 111.66 Mb
PubMed search [1] [2]

MAP/microtubule affinity-regulating kinase 3 is an enzyme that in humans is encoded by the MARK3 gene.[1][2]


MARK3 has been shown to interact with Stratifin.[3][4]


  1. ^ Ono T, Kawabe T, Sonta S, Okamoto T (April 1998). "Assignment of MARK3 alias KP78 to human chromosome band 14q32.3 by in situ hybridization". Cytogenet Cell Genet 79 (1-2): 101–2. doi:10.1159/000134692. PMID 9533022. 
  2. ^ "Entrez Gene: MARK3 MAP/microtubule affinity-regulating kinase 3". 
  3. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  4. ^ Benzinger A, Muster N, Koch HB, Yates JR, Hermeking H (June 2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. 

Further reading[edit]