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MAP/microtubule affinity-regulating kinase 3
Protein MARK3 PDB 1ul7.png
PDB rendering based on 1ul7.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols MARK3 ; CTAK1; KP78; PAR1A; Par-1a
External IDs OMIM602678 MGI1341865 HomoloGene55653 IUPHAR: 2099 ChEMBL: 5600 GeneCards: MARK3 Gene
EC number
Species Human Mouse
Entrez 4140 17169
Ensembl ENSG00000075413 ENSMUSG00000007411
UniProt P27448 Q03141
RefSeq (mRNA) NM_001128918 NM_021516
RefSeq (protein) NP_001122390 NP_067491
Location (UCSC) Chr 14:
103.39 – 103.5 Mb
Chr 12:
111.57 – 111.66 Mb
PubMed search [1] [2]

MAP/microtubule affinity-regulating kinase 3 is an enzyme that in humans is encoded by the MARK3 gene.[1][2]


MARK3 has been shown to interact with Stratifin.[3][4]


  1. ^ Ono T, Kawabe T, Sonta S, Okamoto T (April 1998). "Assignment of MARK3 alias KP78 to human chromosome band 14q32.3 by in situ hybridization". Cytogenet Cell Genet 79 (1-2): 101–2. doi:10.1159/000134692. PMID 9533022. 
  2. ^ "Entrez Gene: MARK3 MAP/microtubule affinity-regulating kinase 3". 
  3. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  4. ^ Benzinger A, Muster N, Koch HB, Yates JR, Hermeking H (June 2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell Proteomics 4 (6): 785–95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. 

Further reading[edit]