METTL3

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METTL3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases METTL3, IME4, M6A, MT-A70, Spo8, methyltransferase like 3, hMETTL3
External IDs MGI: 1927165 HomoloGene: 10501 GeneCards: METTL3
Gene location (Human)
Chromosome 14 (human)
Chr. Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for METTL3
Genomic location for METTL3
Band 14q11.2 Start 21,498,133 bp[1]
End 21,511,375 bp[1]
RNA expression pattern
PBB GE METTL3 209265 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019852

NM_019721

RefSeq (protein)

NP_062826

NP_062695

Location (UCSC) Chr 14: 21.5 – 21.51 Mb Chr 14: 52.29 – 52.31 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

N6-adenosine-methyltransferase 70 kDa subunit is an enzyme that in humans is encoded by the METTL3 gene.[5]

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.[5]

References[edit]

Further reading[edit]