MFAP2

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MFAP2
Identifiers
AliasesMFAP2, MAGP, MAGP-1, MAGP1, microfibrillar associated protein 2, microfibril associated protein 2
External IDsMGI: 99559 HomoloGene: 1801 GeneCards: MFAP2
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for MFAP2
Genomic location for MFAP2
Band1p36.13Start16,974,502 bp[1]
End16,980,835 bp[1]
RNA expression pattern
PBB GE MFAP2 203417 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135247
NM_001135248
NM_002403
NM_017459

NM_001161799
NM_008546
NM_001369292

RefSeq (protein)

NP_001128719
NP_001128720
NP_002394
NP_059453

NP_001155271
NP_032572
NP_001356221

Location (UCSC)Chr 1: 16.97 – 16.98 MbChr 4: 141.01 – 141.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Microfibrillar-associated protein 2 is a protein that in humans is encoded by the MFAP2 gene.[5][6]

Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. This gene encodes two transcripts with two alternatively spliced 5' untranslated exons. These two transcripts contain the same 8 coding exons, and therefore, encode the same protein.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000117122 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060572 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Faraco J, Bashir M, Rosenbloom J, Francke U (Jun 1995). "Characterization of the human gene for microfibril-associated glycoprotein (MFAP2), assignment to chromosome 1p36.1-p35, and linkage to D1S170". Genomics. 25 (3): 630–7. doi:10.1016/0888-7543(95)80004-6. PMID 7759096.
  6. ^ a b "Entrez Gene: MFAP2 microfibrillar-associated protein 2".

Further reading[edit]