MIB1 (gene)

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MIB1 marker also used for detection of grades of astrocytoma

MIB1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MIB1, DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6, mindbomb E3 ubiquitin protein ligase 1
External IDs MGI: 2443157 HomoloGene: 10810 GeneCards: MIB1
RNA expression pattern
PBB GE MIB1 gnf1h02349 at fs.png

PBB GE MIB1 gnf1h08014 at fs.png

PBB GE MIB1 gnf1h08614 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020774

NM_144860

RefSeq (protein)

NP_065825

NP_659109.2
NP_659109

Location (UCSC) Chr 18: 21.7 – 21.87 Mb Chr 18: 10.73 – 10.82 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene.[3] It is involved in regulating apoptosis.[4]

Confusion with proliferative marker[edit]

An antibody directed at the protein Ki-67, a product of the MKI67 gene, is called MIB-1.[5] The MIB1 gene, which regulates apoptosis, should not be confused with the MIB-1 antibody, which is used to measure Ki-67 expression.


References[edit]

Further reading[edit]