MK-9470

MK-9470
Names
	IUPAC name N-((2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl)-2-methyl-2-(5-methylpyridin-2-yloxy)propanamide
Identifiers
CAS Number	945850-36-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	9342440 ;
PubChem CID	11167344;
	InChI InChI=1S/C29H33N3O3/c1-6-34-25-13-11-22(12-14-25)17-26(24-9-7-8-23(16-24)18-30)21(3)32-28(33)29(4,5)35-27-15-10-20(2)19-31-27/h7-16,19,21,26H,6,17H2,1-5H3,(H,32,33)/t21-,26+/m0/s1 Key: JWBGLSNXGRDLKH-HFZDXXHNSA-N ; InChI=1/C29H33N3O3/c1-6-34-25-13-11-22(12-14-25)17-26(24-9-7-8-23(16-24)18-30)21(3)32-28(33)29(4,5)35-27-15-10-20(2)19-31-27/h7-16,19,21,26H,6,17H2,1-5H3,(H,32,33)/t21-,26+/m0/s1 Key: JWBGLSNXGRDLKH-HFZDXXHNBD;
	SMILES C[C@H](N([H])C(C(C)(C)Oc1ncc(C)cc1)=O)[C@@H](Cc2ccc(OCC)cc2)c3cccc(C#N)c3;
Properties
Chemical formula	C29H33N3O3
Molar mass	471.59 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

MK-9470 is a synthetic compound, which binds to the CB₁ cannabinoid receptor and functions as an inverse agonist.^[1]

References

^ Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ (2007). "[¹⁸F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor". Proc. Natl. Acad. Sci. U.S.A. 104 (23): 9800–5. Bibcode:2007PNAS..104.9800B. doi:10.1073/pnas.0703472104. PMC 1877985. PMID 17535893.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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