MKNK2

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MKNK2
Protein MKNK2 PDB 2ac3.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases MKNK2, GPRK7, MNK2, MAP kinase interacting serine/threonine kinase 2
External IDs MGI: 894279 HomoloGene: 49674 GeneCards: MKNK2
RNA expression pattern
PBB GE MKNK2 218205 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_199054
NM_017572

NM_021462

RefSeq (protein)

NP_060042
NP_951009

NP_067437.2
NP_067437

Location (UCSC) Chr 19: 2.04 – 2.05 Mb Chr 10: 80.67 – 80.68 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

MAP kinase-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the MKNK2 gene.[3][4]


Interactions[edit]

MKNK2 has been shown to interact with MAPK1[5][6] and Eukaryotic translation initiation factor 4 gamma.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Slentz-Kesler K, Moore JT, Lombard M, Zhang J, Hollingsworth R, Weiner MP (Oct 2000). "Identification of the human Mnk2 gene (MKNK2) through protein interaction with estrogen receptor beta". Genomics. 69 (1): 63–71. doi:10.1006/geno.2000.6299. PMID 11013076. 
  4. ^ "Entrez Gene: MKNK2 MAP kinase interacting serine/threonine kinase 2". 
  5. ^ a b Scheper, Gert C; Parra Josep L; Wilson Mary; Van Kollenburg Barbara; Vertegaal Alfred C O; Han Ze-Guang; Proud Christopher G (Aug 2003). "The N and C termini of the splice variants of the human mitogen-activated protein kinase-interacting kinase Mnk2 determine activity and localization". Mol. Cell. Biol. United States. 23 (16): 5692–705. doi:10.1128/MCB.23.16.5692-5705.2003. ISSN 0270-7306. PMC 166352Freely accessible. PMID 12897141. 
  6. ^ Waskiewicz, A J; Flynn A; Proud C G; Cooper J A (Apr 1997). "Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2". EMBO J. ENGLAND. 16 (8): 1909–20. doi:10.1093/emboj/16.8.1909. ISSN 0261-4189. PMC 1169794Freely accessible. PMID 9155017. 

Further reading[edit]