MKRN3

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MKRN3
Identifiers
AliasesMKRN3, CPPB2, D15S9, RNF63, ZFP127, ZNF127, makorin ring finger protein 3
External IDsOMIM: 603856 MGI: 2181178 HomoloGene: 4143 GeneCards: MKRN3
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for MKRN3
Genomic location for MKRN3
Band15q11.2Start23,565,674 bp[1]
End23,630,075 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005664

NM_011746

RefSeq (protein)

NP_005655

NP_035876

Location (UCSC)Chr 15: 23.57 – 23.63 MbChr 7: 62.42 – 62.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Makorin ring finger protein 3 is a protein that in humans is encoded by the MKRN3 gene.[5]

Function[edit]

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader–Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000179455 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070527 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Makorin ring finger protein 3". Retrieved 2017-06-12.

Further reading[edit]


This article incorporates text from the United States National Library of Medicine, which is in the public domain.