MNX1

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
MNX1
Identifiers
AliasesMNX1, HB9, HLXB9, HOXHB9, SCRA1, motor neuron and pancreas homeobox 1
External IDsMGI: 109160 HomoloGene: 21137 GeneCards: MNX1
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for MNX1
Genomic location for MNX1
Band7q36.3Start156,994,051 bp[1]
End157,010,663 bp[1]
RNA expression pattern
PBB GE HLXB9 214614 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005515
NM_001165255

NM_019944

RefSeq (protein)

NP_001158727
NP_005506

NP_064328

Location (UCSC)Chr 7: 156.99 – 157.01 MbChr 5: 29.47 – 29.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Motor neuron and pancreas homeobox 1 (MNX1), also known as Homeobox HB9 (HLXB9), is a human protein encoded by the MNX1 gene.[5]

Clinical significance[edit]

Mutations in the MNX1 gene are associated with Currarino syndrome.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130675 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001566 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: HLXB9 homeobox HB9".
  6. ^ Merello E, De Marco P, Ravegnani M, Riccipetitoni G, Cama A, Capra V (2013). "Novel MNX1 mutations and clinical analysis of familial and sporadic Currarino cases". Eur J Med Genet. 56 (12): 648–54. doi:10.1016/j.ejmg.2013.09.011. PMID 24095820.

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.